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SUB1 antibody

SUB1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7261886
  • Target See all SUB1 Antibodies
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    Reactivity
    • 34
    • 12
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 32
    • 2
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 23
    • 3
    • 3
    • 3
    • 1
    • 1
    This SUB1 antibody is un-conjugated
    Application
    • 29
    • 18
    • 14
    • 7
    • 6
    • 4
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human PABPC4 (NP_003810.1).
    Isotype
    IgG
    Top Product
    Discover our top product SUB1 Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    Alternative Name
    PC4 (SUB1 Products)
    Synonyms
    P15 antibody, PC4 antibody, p14 antibody, AI842364 antibody, P9 antibody, Pc4 antibody, Rpo2tc1 antibody, SUB1 homolog, transcriptional regulator antibody, SUB1 homolog (S. cerevisiae) antibody, SUB1 antibody, Sub1 antibody
    Background
    Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Gene ID
    8761
    UniProt
    Q13310
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