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C8orf4 antibody

C8orf4 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7262064
  • Target See all C8orf4 Antibodies
    C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
    Reactivity
    • 27
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 27
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C8orf4 antibody is un-conjugated
    Application
    • 18
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human C8orf4 (NP_064515.1).
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
    Alternative Name
    C8orf4 (C8orf4 Products)
    Synonyms
    TC-1 antibody, TC1 antibody, 1110065B09Rik antibody, AW121743 antibody, AW321058 antibody, C8ORF4 antibody, transcriptional and immune response regulator antibody, chromosome 22 open reading frame, human C8orf4 antibody, TCIM antibody, C22H8ORF4 antibody, Tcim antibody
    Background
    This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
    Gene ID
    56892
    UniProt
    Q9NR00
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