Deoxyguanosine Kinase antibody

Catalog No. ABIN7262793

The Rabbit Polyclonal anti-Deoxyguanosine Kinase antibody is suitable to detect Deoxyguanosine Kinase in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for Deoxyguanosine Kinase antibody (ABIN7262793)

Target: Deoxyguanosine Kinase (DGUOK)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deoxyguanosine Kinase antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Deoxyguanosine Kinase Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human DGUOK (NP_550438.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Deoxyguanosine Kinase

Target: Deoxyguanosine Kinase (DGUOK)

Alternative Name: DGUOK

Background: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Gene ID: 1716

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process