PDE6B antibody
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- Target See all PDE6B Antibodies
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE6B antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PDE6B (NP_001138763.1).
- Isotype
- IgG
- Top Product
- Discover our top product PDE6B Primary Antibody
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anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 1-190) antibody
PDE6B Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 1-853) antibodyPDE6B Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 372-421) antibodyPDE6B Reactivity: Human, Cow, Dog, Horse WB Host: Rabbit Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) (AA 105-154) antibodyPDE6B Reactivity: Human, Cow, Dog, Horse, Rabbit, Guinea Pig, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B) antibodyPDE6B Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
- Alternative Name
- PDE6B (PDE6B Products)
- Synonyms
- CSNB3 antibody, CSNBAD2 antibody, PDEB antibody, RP40 antibody, rd1 antibody, PDBS antibody, RCD-1 antibody, Pdeb antibody, r antibody, rd antibody, rd-1 antibody, rd10 antibody, phosphodiesterase 6B antibody, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide antibody, PDE6B antibody, Pde6b antibody
- Background
- Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene ID
- 5158
- UniProt
- P35913
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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