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LFNG antibody

LFNG Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7011788
  • Target See all LFNG Antibodies
    LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))
    Reactivity
    • 37
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 29
    • 8
    Rabbit
    Clonality
    • 31
    • 6
    Polyclonal
    Conjugate
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LFNG antibody is un-conjugated
    Application
    • 27
    • 25
    • 16
    • 12
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human LFNG (NP_002295.1).
    Isotype
    IgG
    Top Product
    Discover our top product LFNG Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))
    Alternative Name
    LFNG (LFNG Products)
    Synonyms
    SCDO3 antibody, AW061165 antibody, id:ibd2614 antibody, id:ibd5029 antibody, id:ibd5138 antibody, l-fng antibody, wu:fc69h02 antibody, wu:fi34c01 antibody, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase S homeolog antibody, LFNG antibody, Lfng antibody, lfng.S antibody, lfng antibody
    Background
    This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene.
    Gene ID
    3955
    UniProt
    Q8NES3
    Pathways
    Notch Signaling
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