PPP2R3B antibody

Catalog No. ABIN7264535

This anti-PPP2R3B antibody is a Rabbit Polyclonal antibody detecting PPP2R3B in WB. Suitable for Human and Mouse.

Quick Overview for PPP2R3B antibody (ABIN7264535)

Target: PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP2R3B Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PPP2R3B (NP_037371.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPP2R3B

Target: PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))

Alternative Name: PPP2R3B

Background: Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''.

Molecular Weight:

Observed_MW: 80 kDa

Calculated_MW: 20 kDa/65 kDa

Gene ID: 28227

UniProt: Q9Y5P8

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases