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ARHGEF3 antibody

ARHGEF3 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7264537
  • Target See all ARHGEF3 Antibodies
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    Reactivity
    • 34
    • 4
    • 4
    • 1
    Human, Mouse
    Host
    • 31
    • 3
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF3 antibody is un-conjugated
    Application
    • 25
    • 22
    • 19
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ARHGEF3 (NP_062455.1).
    Isotype
    IgG
    Top Product
    Discover our top product ARHGEF3 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    Alternative Name
    ARHGEF3 (ARHGEF3 Products)
    Synonyms
    MGC82822 antibody, ARHGEF3 antibody, si:ch211-258l4.8 antibody, MGC108040 antibody, DKFZp459N027 antibody, GEF3 antibody, STA3 antibody, XPLN antibody, 1200004I24Rik antibody, 9830169H03Rik antibody, C76747 antibody, Xpln antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog antibody, Rho guanine nucleotide exchange factor 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 antibody, arhgef3.1.S antibody, ARHGEF3 antibody, arhgef3 antibody, arhgef3.1 antibody, Arhgef3 antibody
    Background
    Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 60 kDa

    Calculated_MW: 36 kDa/59 kDa/60 kDa/63 kDa

    Gene ID
    50650
    UniProt
    Q9NR81
    Pathways
    Neurotrophin Signaling Pathway
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