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DLL4 antibody (PE)

This anti-DLL4 antibody is a Mouse Monoclonal antibody detecting DLL4 in FACS. Suitable for Human.
Catalog No. ABIN7013930

Quick Overview for DLL4 antibody (PE) (ABIN7013930)

Target

See all DLL4 Antibodies
DLL4 (delta-Like 4 (DLL4))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This DLL4 antibody is conjugated to PE

Application

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Flow Cytometry (FACS)

Clone

MHD4-46
  • Purpose

    Anti-DLL4 PE

    Specificity

    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

    Purification

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    recombinant soluble human DLL4

    Isotype

    IgG1 kappa
  • Application Notes

    Flow cytometry: Recommended dilution: 1-5 μg/mL

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target

    DLL4 (delta-Like 4 (DLL4))

    Alternative Name

    DLL4

    Background

    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4

    Gene ID

    54567

    UniProt

    Q9NR61

    Pathways

    Notch Signaling
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