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Mu Opioid Receptor 1 antibody (AA 165-270)

OPRM1 Reactivity: Mouse, Rat ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed (2 references)
Catalog No. ABIN701755
$384.62
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target See all Mu Opioid Receptor 1 (OPRM1) Antibodies
    Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))
    Binding Specificity
    • 27
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 165-270
    Reactivity
    • 63
    • 47
    • 22
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 79
    • 3
    • 2
    Rabbit
    Clonality
    • 83
    • 1
    Polyclonal
    Conjugate
    • 43
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Mu Opioid Receptor 1 antibody is un-conjugated
    Application
    • 52
    • 40
    • 34
    • 18
    • 13
    • 10
    • 9
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    Human,Dog,Cow,Pig,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human mu Opioid receptor
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Wu, Li, Wu: "The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats." in: Sleep & breathing = Schlaf & Atmung, Vol. 21, Issue 1, pp. 227-233, (2017) (PubMed).

    Laureano, Dalle Molle, Alves, Luft, Desai, Ross, Silveira: "Intrauterine growth restriction modifies the hedonic response to sweet taste in newborn pups - Role of the accumbal μ-opioid receptors." in: Neuroscience, Vol. 322, pp. 500-8, (2016) (PubMed).

  • Target
    Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))
    Alternative Name
    mu Opioid receptor (OPRM1 Products)
    Synonyms
    LMOR antibody, M-OR-1 antibody, MOP antibody, MOR antibody, MOR1 antibody, OPRM antibody, MOP-R antibody, MOR-1 antibody, MOR-1O antibody, Oprm antibody, mor antibody, muOR antibody, MORA antibody, Oprrm1 antibody, or2 antibody, ZFOR2 antibody, OPRM1 antibody, opioid receptor mu 1 antibody, opioid receptor, mu 1 antibody, outer membrane protein OprM antibody, OPRM1 antibody, Oprm1 antibody, oprm1 antibody, oprM1 antibody
    Background

    This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: MOP, MOR, LMOR, MOR1, OPRM, M-OR-1, Mu-type opioid receptor, MOR-1, Mu opiate receptor, Mu opioid receptor, hMOP, OPRM1

    Gene ID
    4988
    UniProt
    P35372
    Pathways
    cAMP Metabolic Process, Synaptic Membrane
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