DACH2 antibody (AA 501-599) (HRP)

Catalog No. ABIN702259

This Rabbit Polyclonal antibody specifically detects DACH2 in WB, ELISA, IHC (fro), IHC (p). It exhibits reactivity toward Human.

Quick Overview for DACH2 antibody (AA 501-599) (HRP) (ABIN702259)

Target: DACH2 (Dachshund 2 (DACH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DACH2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DACH2 Antibody (HRP)

Binding Specificity: AA 501-599

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DACH2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DACH2

Target: DACH2 (Dachshund 2 (DACH2))

Alternative Name: DACH2

Background:

Synonyms: DACH 2, dachshund 2, Dachshund homolog 2 Drosophila, Dachshund homolog 2, Dachshund2, FLJ31391, HGNC:16814, MGC138545.

Background: DACH2 is a transcription factor that is involved in regulation of organogenesis. It seems to be a regulator for SIX1 and SIX6 and may act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. It probably binds to DNA via its DACH box-N domain.

Gene ID: 117154