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DACH2 antibody

DACH2 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7113311
  • Target See all DACH2 Antibodies
    DACH2 (Dachshund 2 (DACH2))
    Reactivity
    • 34
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 34
    • 1
    • 1
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DACH2 antibody is un-conjugated
    Application
    • 34
    • 17
    • 13
    • 13
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    dachshund homolog 2(Drosophila)
    Isotype
    IgG
    Top Product
    Discover our top product DACH2 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    DACH2 (Dachshund 2 (DACH2))
    Alternative Name
    DACH2 (DACH2 Products)
    Synonyms
    9430028N04Rik antibody, RGD1561687 antibody, dachshund family transcription factor 2 antibody, dachshund 2 (Drosophila) antibody, dachshund family transcription factor 2 L homeolog antibody, dachshund homolog 2 antibody, dachshund homolog 2 (Drosophila) antibody, DACH2 antibody, Dach2 antibody, dach2.L antibody, LOC612847 antibody, dach2 antibody
    Background
    Synonyms: Background:Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression(By similarity). Probably binds to DNA via its DACHbox-N domain.
    Molecular Weight
    65 kDa
    Gene ID
    117154
    UniProt
    Q96NX9
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