Claudin 6 antibody (pTyr219) (HRP)

Catalog No. ABIN703399

This Rabbit Polyclonal antibody specifically detects Claudin 6 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Claudin 6 antibody (pTyr219) (HRP) (ABIN703399)

Target: Claudin 6 (CLDN6)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 6 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Claudin 6 Antibody (HRP)

Binding Specificity: pTyr219

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Claudin 6 around the phosphorylation site of Tyr219

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Claudin 6

Target: Claudin 6 (CLDN6)

Alternative Name: Claudin 6

Background:

Synonyms: Claudin6, CLDN 6, CLDN6, Skullin 2, CLD6_HUMAN.

Background: Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.

Gene ID: 9074

Pathways: Hepatitis C