Galanin Receptor 1 antibody (1st Extracellular Loop)

Catalog No. ABIN7886411

The Rabbit Polyclonal anti-Galanin Receptor 1 antibody is suitable to detect Galanin Receptor 1 in samples from Mouse. It has been validated for WB, IF, IHC and IC.

Quick Overview for Galanin Receptor 1 antibody (1st Extracellular Loop) (ABIN7886411)

Target: Galanin Receptor 1 (GALR1)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galanin Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunochromatography (IC)

Product Details anti-Galanin Receptor 1 Antibody

Binding Specificity: 1st Extracellular Loop, AA 60-71

Purpose: A Rabbit Polyclonal Antibody to Galanin Receptor Type 1

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Rat,human - identical

Characteristics: Anti-GALR1 Antibody (ABIN7043180 and ABIN7044397) is a highly specific antibody directed against an epitope of the mouse Galanin receptor 1. The antibody can be used in western blot, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize GALR1 from mouse, rat, and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogen: RSKPGKPRSTTN(C), corresponding to amino acid residues 60-71 of mouse Galanin receptor type 1

Isotype: IgG

Application Details

Application Notes:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: 1:100

IHC: 1:200

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7235473)

Blocking Peptide: (ABIN7235473)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for Galanin Receptor 1

Target: Galanin Receptor 1 (GALR1)

Alternative Name: GALR1

Background:

Synonyms: Galanin receptor type 1, GALNR1, GAL1R

Description: Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known receptors, the Galanin receptor type 1 (GALR1), Galanin receptor type 2 (GALR2) and Galanin receptor type 3 (GALR3). The Galanin receptors belong to the G-protein coupled receptor superfamily.1-4Based on mRNA, the GALR1 is predominantly distributed in the central nervous system, spinal cord and dorsal root ganglia while GALR2 is abundant in both central and peripheral nervous systems. GALR3 mRNA is distributed in peripheral tissues such as the heart, spleen, and testis. However, its expression in the brain is still controversial.4,5

Gene ID: 14427

NCBI Accession: NM_001480

UniProt: P56479

Pathways: cAMP Metabolic Process