MMGT1 antibody (C-Term, Intracellular)

Catalog No. ABIN7886800

This Rabbit Polyclonal antibody specifically detects MMGT1 in WB. It exhibits reactivity toward Rat.

Quick Overview for MMGT1 antibody (C-Term, Intracellular) (ABIN7886800)

Target: MMGT1 (Membrane Magnesium Transporter 1 (MMGT1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMGT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMGT1 Antibody

Binding Specificity: AA 118-131, C-Term, Intracellular

Purpose: A Rabbit Polyclonal Antibody to Membrane Magnesium Transporter MMgT1

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Mouse - identical, human - 12,14 amino acid residues identical

Characteristics: Anti-MMGT1 Antibody is directed against an epitope of rat membrane magnesium transporter 1. Anti-MMGT1 Antibody(ABIN7043329, ABIN7044853 and ABIN7044854) can be used in western blot analysis. It has been designed to recognize MMgT1 from mouse, rat and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogen: (C)NTSLKLRKFDSLRR, corresponding to amino acid residues 118-131 of rat MMGT1

Isotype: IgG

Application Details

Application Notes:

WB: 1:400

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7235948)

Blocking Peptide: (ABIN7235948)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for MMGT1

Target: MMGT1 (Membrane Magnesium Transporter 1 (MMGT1))

Alternative Name: MMGT1

Background:

Synonyms: Membrane magnesium transporter 1, ER membrane protein complex subunit 5, Transmembrane protein 32, Emc5, Tmem32

Description: The MMgT gene family is comprised of two members: MMgT1 (membrane Mg2+ transporter 1) and MMgT2 (membrane Mg2+ transporter 2). Both proteins mediate Mg2+ uptake when expressed in Xenopus laevis oocytes. An increase in MMgT1 and MMgT2 transcripts is detected when there are low levels of Mg2+. There are two predicted transmembrane domains suggesting that the protein can form functional oligomers. It has been suggested that it may form homo- and, perhaps, heterooligomeric units.MMgT1 can be found in the cell in golgi complex and post-golgi vesicles. The protein is expressed in a wide variety of tissues including in the liver and brain and more abundant expression in the heart muscle and kidney is observed. Very small amounts of transcripts are detected in the intestine and colon.

Gene ID: 302864

NCBI Accession: NM_173470

UniProt: B5DF51