KCNK15 antibody (1st Extracellular Loop)

Catalog No. ABIN7886953

The Rabbit Polyclonal anti-KCNK15 antibody (ABIN7886953) specifically detects KCNK15 in WB. The antibody is reactive with Rat samples.

Quick Overview for KCNK15 antibody (1st Extracellular Loop) (ABIN7886953)

Target: KCNK15 (Potassium Channel Subfamily K Member 15 (KCNK15))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNK15 Antibody

Binding Specificity: 1st Extracellular Loop, AA 43-57

Purpose: A Rabbit Polyclonal Antibody to KCNK15 Channel

Cross-Reactivity: Mouse, Rat

Cross-Reactivity (Details): Not recommended for human samples

Predicted Reactivity: Mouse - identical

Characteristics: Anti-KCNK15 (extracellular) Antibody is directed against an epitope of the rat KCNK15 channel. Anti-KCNK15 (extracellular) Antibody (ABIN7043445, ABIN7045054 and ABIN7045055) can be used in western blot analysis. The antibody recognizes an extracellular epitope and is thus ideal for detecting the channel in living cells. It has been designed to recognize KCNK15 from rat and mouse samples. The antibody will unlikely recognize the channel from human samples.

Purification: Affinity purified on immobilized antigen.

Immunogen: (C)RKRGEFRRKYRFSAD, corresponding to amino acid residues 43-57 of rat KCNK15 

Isotype: IgG

Application Details

Application Notes:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Comment:

Negative Control: (ABIN7236292)

Blocking Peptide: (ABIN7236292)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Target Details for KCNK15

Target: KCNK15 (Potassium Channel Subfamily K Member 15 (KCNK15))

Alternative Name: KCNK15

Background:

Synonyms: Potassium channel subfamily K member 15, Acid-sensitive K+ channel protein TASK-5, TWIK-related acid-sensitive K+ channel 5, K2P15.1

Description: TASK1-5 are members of the two-pore domain K+ channels. They have four transmembrane domains and assist in setting the resting membrane potential.TASK5 (K2P15.1, KCNK15) was identified using the TASK-3 sequence in a GenBank search. However, when expressed in COS-7 cells, it does not form a functional K+ current1.The channel is distributed in the brain, heart, lung, kidney, liver, pancreas, adrenal gland and placenta2.

Gene ID: 156873

NCBI Accession: NM_022358

UniProt: Q8R5I0