Recombinant GPIIb/IIIa (Abciximab Biosimilar) antibody
Quick Overview for Recombinant GPIIb/IIIa (Abciximab Biosimilar) antibody (ABIN7072232)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-CD41 [7E3 (Abciximab)], Human IgG1, kappa
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Specificity
- Recognises human CD41.
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Characteristics
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Original Species of Ab: Human
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogen
- CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a reformatted human IgG1 antibody based on the therapeutic Fab fragment. NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- GPIIb/IIIa (Abciximab Biosimilar)
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Target Type
- Biosimilar
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Background
- Integrin alpha-IIb, Integrin alpha-2b, ITGA2B, platelet glycoprotein IIb of IIb/IIIa complex
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UniProt
- P08514
Target
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