Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) antibody

Catalog No. ABIN7072319

The Mouse Monoclonal anti-Discoidin Domain Receptor 1 antibody is suitable to detect Discoidin Domain Receptor 1 in samples from Human. It has been validated for BP, ELISA and WB.

Quick Overview for Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) antibody (ABIN7072319)

Target: Discoidin Domain Receptor 1

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Blocking Peptide (BP), ELISA, Western Blotting (WB)

Clone: 3E3

Product Details

Binding Specificity: Extracellular Domain

Purpose: Anti-Discoidin Domain Receptor 1 [3E3], Mouse IgG1, kappa

Specificity: This antibody binds specifically to the extracellular domain of human DDR1.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2

Purification: Protein A affinity purified

Immunogen: Recombinant human DDR1 extracellular domain.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody binds to human Discoidin Domain Receptor 1, a receptor tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates the attachemnt of the cell to the extracellular matrix. This receptor is required for blastocyst implantation during pregnancy, mammary gland differentiation as well as lactation. It promotes smooth muscle cell migration as well as tumour cell invasion. The antibody acts as an antagonist.

Comment:

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details

Target: Discoidin Domain Receptor 1

Background: DDR1

UniProt: Q08345