Recombinant CD74 antibody

Catalog No. ABIN7072421

The Rat Monoclonal anti-CD74 antibody is suitable to detect CD74 in samples from Mouse. It has been validated for FACS, IP and IHC (fro).

Quick Overview for Recombinant CD74 antibody (ABIN7072421)

Target: CD74 (HLA-DR-gamma (CD74))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD74 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: In-1

Product Details anti-CD74 Antibody

Purpose: Anti-CD74 [In-1], Rat IgG2b, kappa

Specificity: This antibody binds to murine CD74.

Characteristics:

Original Species of Ab: Rat

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogen: Mouse lymphocytes of strain A injected into Wistar rats.

Isotype: IgG2b kappa

Application Details

Application Notes: The In-1 antibody was used to identify CD74 on lymphocytes in mice. It can be used in immunoprecipitation as well as in flow cytometry (Takahashi et al. 2009, PMID: 19413900) and frozen-section IHC (Momburg et al. 1986, PMID: 3079804).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD74

Target: CD74 (HLA-DR-gamma (CD74))

Alternative Name: CD74

Background: Ia antigen, DHLAG, HLADG, Ia-gamma, H-2 class II histocompatibility antigen gamma chain, CLIP, LN-1, LN1, IN1

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints