Recombinant IL2 Receptor beta antibody

Catalog No. ABIN7072573

This Rabbit Chimeric antibody specifically detects IL2 Receptor beta in FACS. It exhibits reactivity toward Mouse.

Quick Overview for Recombinant IL2 Receptor beta antibody (ABIN7072573)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Chimeric

Conjugate: This IL2 Receptor beta antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 5H4

Product Details anti-IL2 Receptor beta Antibody

Purpose: Anti-IL2R beta [5H4], Rabbit IgG, kappa

Specificity: This antibody is specific for the murine interleukin-2 receptor beta chain.

Characteristics:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunising Lewis rats with transfected rat myeloma cell line YB2/0, expressing truncated murine IL-2R beta.

Isotype: IgG kappa

Application Details

Application Notes: This antibody has been used in flow cytometric analysis of IL-2R beta expression by thymocytes, lymph node cells and 3B4.15 T hybridoma cells (Ligons et al, 2012), as well as NK cells (He et al, 1996, Frenkel et al, 2016, Put et al, 2016, Elkabets et al, 2009).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Alternative Name: IL2R beta

Background: CD122, IL-2Rβ, IL-2 receptor subunit beta, Interleukin-2 receptor subunit beta, High affinity IL-2 receptor subunit beta, p70-75

UniProt: P16297

Pathways: JAK-STAT Signaling, Growth Factor Binding