Recombinant beta 2 Adrenergic Receptor antibody
Quick Overview for Recombinant beta 2 Adrenergic Receptor antibody (ABIN7072669)
Target
See all beta 2 Adrenergic Receptor (ADRB2) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Beta 2 adrenergic receptor [R11/E1], Rabbit IgG, kappa
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Specificity
- R11/E1 antibody recognizes human beta-2 adrenergic receptor. Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds adrenaline with far grater affinity than noradrenaline.
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Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogen
- This antibody was raised by immunizing mice with beta-2 adrenergic receptor.
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Isotype
- IgG kappa
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Application Notes
- This antibody is recommended for the detection and analysis of the beta-2 adrenergic receptor. It was successfully used in the in vivo phosphorylation assays during Western blot detections of beta-2 adrenergic receptor (Huang et al., 2009).
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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Alternative Name
- Beta 2 adrenergic receptor
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Background
- R11E1, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, β-2 adrenergic receptor, β-2 adrenoreceptor, β-2 adrenoceptor, β2AR, β2-AR
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UniProt
- P07550
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Pathways
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
Target
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