Recombinant SETD7 antibody

Catalog No. ABIN7072703

The Rabbit Chimeric anti-SETD7 antibody is suitable to detect SETD7 in samples from Human. It has been validated for ELISA, FACS, IF, IP, ChIP and MS.

Quick Overview for Recombinant SETD7 antibody (ABIN7072703)

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This SETD7 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Mass Spectrometry (MS)

Clone: RAB-C220

Product Details anti-SETD7 Antibody

Purpose: Anti-SETD7 [RAB-C220], Rabbit IgG, kappa

Specificity: This antibody recognizes SETD7 (Histone-lysine N-methyltransferase SETD7). It binds to a folded domain, amino acids 2-366. SETD7 is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It plays a central role in the transcriptional activation of genes such as collagenase or insulin.

Characteristics:

Original Species of Ab: Human

Original Format of Ab: Fab

Purification: Protein A affinity purified

Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing SETD7 protein under non-denaturing conditions.

Isotype: IgG kappa

Application Details

Application Notes: This antibody has been used and recommended for the following methods: ELISA, IF, spiked IP, IP-MS, ChIP, FC.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for SETD7

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Alternative Name: SETD7

Background: SET7/9, Histone-lysine N-methyltransferase SETD7, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, anti-SETD7-RAB-C220, 48H1_2

UniProt: Q8WTS6