BEND3 antibody
Quick Overview for BEND3 antibody (ABIN7073204)
Target
See all BEND3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Cross-Reactivity
- Human, Rat
-
Purification
- Affinity purification
-
Immunogen
- Recombinant protein corresponding to Mouse BEND3
-
-
-
-
Application Notes
- WB (H,M,R) 1:500-1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
-
- BEND3 (BEN Domain Containing 3 (BEND3))
-
Alternative Name
- BEND3
-
Background
- The BEND3 is a transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination. Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites.
-
Molecular Weight
- 100 kDa
-
Gene ID
- 331623
-
NCBI Accession
- NP_950193
-
UniProt
- Q6PAL0
Target
-