CACNA1I antibody

Catalog No. ABIN7073274

The Rabbit Polyclonal anti-CACNA1I antibody is suitable to detect CACNA1I in samples from Rat. It has been validated for WB.

Quick Overview for CACNA1I antibody (ABIN7073274)

Target: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1I antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CACNA1I Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Ca(v)3.3

Application Details

Application Notes: WB (R) 1:300-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CACNA1I

Target: CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))

Alternative Name: Ca(v)3.3

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle.

Molecular Weight: 250 kDa

UniProt: E9Q7P2