Radixin antibody (AA 25-130) (Biotin)

Catalog No. ABIN704428

This Rabbit Polyclonal antibody specifically detects Radixin in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for Radixin antibody (AA 25-130) (Biotin) (ABIN704428)

Target: Radixin (RDX)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Radixin antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Radixin Antibody (Biotin)

Binding Specificity: AA 25-130

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Radixin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Radixin

Target: Radixin (RDX)

Alternative Name: Radixin

Background:

Synonyms: ESP10, Hh-induced MATH and BTB domain-containing protein, HIB, Moesin-B, Protein roadkill, Radixin, rdx, CB567, CG12537, DFNB24, RADI_HUMAN.

Background: Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID: 5962

Pathways: Regulation of Actin Filament Polymerization, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome