CHD1L antibody

Catalog No. ABIN7073491

The Rabbit Polyclonal anti-CHD1L antibody (ABIN7073491) specifically detects CHD1L in IF and IHC. The antibody is reactive with Mouse and Rat samples.

Quick Overview for CHD1L antibody (ABIN7073491)

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD1L antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-CHD1L Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinantproteincorresponding to Mouse CHD1L

Application Details

Application Notes: IHC/IF (M,R) 1:600-1:2000/1:600-1:1200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CHD1L

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Alternative Name: CHD1L

Background: In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes, and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage.DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair.

Gene ID: 68058

NCBI Accession: NP_080815

UniProt: Q9CXF7