CCDC111 antibody

Catalog No. ABIN7073534

This Rabbit Polyclonal antibody specifically detects CCDC111 in IHC, IF and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CCDC111 antibody (ABIN7073534)

Target: CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC111 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)

Product Details anti-CCDC111 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse CCDC111

Application Details

Application Notes: WB (M,R) 1:500-1:1000, IHC/IF (H) 1:700-1:1400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CCDC111

Target: CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))

Alternative Name: Coiled-coil domain-containing protein 111

Background: DNA primase and DNA polymerase required to tolerate replication-stalling lesions by bypassing them . Required to facilitate mitochondrial and nuclear replication fork progression by initiating de novo DNA synthesis using dNTPs and acting as an error-prone DNA polymerase able to bypass certain DNA lesions (By similarity). Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA .

Molecular Weight: 64 kDa

Gene ID: 408022

NCBI Accession: NP_001001184

UniProt: Q6P1E7