eRF3/GSPT1 antibody
-
- Target
- eRF3/GSPT1
- Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse eRF3/GSPT1
-
-
- Application Notes
- WB (H,M,R) 1:500-1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
-
- Target
- eRF3/GSPT1
- Background
- ERF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
- Molecular Weight
- 72 kDa
- Gene ID
- 14852
- NCBI Accession
- NP_001123480
- UniProt
- Q8R050
-