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eRF3/GSPT1 antibody

Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7073859
  • Target
    eRF3/GSPT1
    Reactivity
    Human, Mouse, Rat
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    Un-conjugated
    Application
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse eRF3/GSPT1
  • Application Notes
    WB (H,M,R) 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    eRF3/GSPT1
    Background
    ERF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
    Molecular Weight
    72 kDa
    Gene ID
    14852
    NCBI Accession
    NP_001123480
    UniProt
    Q8R050
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