FBXO42 antibody

Catalog No. ABIN7073905

Product Details anti-FBXO42 Antibody

Target: FBXO42 (F-Box Protein 42 (FBXO42))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO42 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse FBXO42

Application Details

Application Notes: WB (M,R) 1:200-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FBXO42

Target: FBXO42 (F-Box Protein 42 (FBXO42))

Alternative Name: FBXO42 (FBXO42 Products)

Synonyms: Fbx42 antibody, JFK antibody, 6720460I06Rik antibody, mKIAA1332 antibody, zgc:64224 antibody, wu:fj14e08 antibody, MGC84191 antibody, FBXO42 antibody, F-box protein 42 antibody, F-box protein 42 L homeolog antibody, FBXO42 antibody, Fbxo42 antibody, fbxo42 antibody, fbxo42.L antibody

Background: FBXO42 (F-box only protein 42) is a 717 amino acid protein that contains four Kelch repeats and one N-terminal F-box domain, and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination.

Molecular Weight: 75 kDa

Gene ID: 213499

NCBI Accession: NP_766106

UniProt: Q6PDJ6