UBE2R2 antibody (AA 101-200)

Catalog No. ABIN704486

The Rabbit Polyclonal anti-UBE2R2 antibody is suitable to detect UBE2R2 in samples from Human. It has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for UBE2R2 antibody (AA 101-200) (ABIN704486)

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2R2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-UBE2R2 Antibody

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDC34B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for UBE2R2

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Alternative Name: CDC34B/UBC3B

Background:

Synonyms: CDC34B, E2 CDC34B, UBE2R2, Ubiquitin carrier protein R2, Ubiquitin conjugating enzyme E2 CDC34B, Ubiquitin conjugating enzyme E2 R2, Ubiquitin conjugating enzyme E2R 2, Ubiquitin conjugating enzyme UBC3B, Ubiquitin protein ligase R2.

Background: UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Gene ID: 283337