UBE2R2 antibody

Catalog No. ABIN7231988

This Rabbit Polyclonal antibody specifically detects UBE2R2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for UBE2R2 antibody (ABIN7231988)

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2R2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-UBE2R2 Antibody

Purpose: Rabbit Anti-UB2R2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of UB2R2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human UB2R2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBE2R2

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Alternative Name: UB2R2

Background: Ubiquitin-conjugating enzyme E2 R2, E2 ubiquitin-conjugating enzyme R2, Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2UBE2R2 (Ubiquitin Conjugating Enzyme E2 R2) is a Protein Coding gene. Among its related pathways are Protein ubiquitination and Influenza A. Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. UBE2R2 encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Molecular Weight: 26kD

Gene ID: 54926

UniProt: Q712K3