UBE2R2 antibody (AA 101-200) (Biotin)

Catalog No. ABIN704488

This Rabbit Polyclonal antibody specifically detects UBE2R2 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for UBE2R2 antibody (AA 101-200) (Biotin) (ABIN704488)

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2R2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-UBE2R2 Antibody (Biotin)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDC34B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for UBE2R2

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Alternative Name: CDC34B/UBC3B

Background:

Synonyms: CDC34B, E2 CDC34B, UBE2R2, Ubiquitin carrier protein R2, Ubiquitin conjugating enzyme E2 CDC34B, Ubiquitin conjugating enzyme E2 R2, Ubiquitin conjugating enzyme E2R 2, Ubiquitin conjugating enzyme UBC3B, Ubiquitin protein ligase R2.

Background: UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Gene ID: 283337