UBE2R2 antibody (AA 101-200) (FITC)

Catalog No. ABIN704493

This anti-UBE2R2 antibody is a Rabbit Polyclonal antibody detecting UBE2R2 in WB, IF (cc) and IF (p). Suitable for Human.

Quick Overview for UBE2R2 antibody (AA 101-200) (FITC) (ABIN704493)

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2R2 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-UBE2R2 Antibody (FITC)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDC34B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for UBE2R2

Target: UBE2R2 (Ubiquitin-Conjugating Enzyme E2R 2 (UBE2R2))

Alternative Name: CDC34B/UBC3B

Background:

Synonyms: CDC34B, E2 CDC34B, UBE2R2, Ubiquitin carrier protein R2, Ubiquitin conjugating enzyme E2 CDC34B, Ubiquitin conjugating enzyme E2 R2, Ubiquitin conjugating enzyme E2R 2, Ubiquitin conjugating enzyme UBC3B, Ubiquitin protein ligase R2.

Background: UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Gene ID: 283337