GDF5 antibody
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- Target See all GDF5 Antibodies
- GDF5 (Growth Differentiation Factor 5 (GDF5))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GDF5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Rat
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse GDF 5
- Top Product
- Discover our top product GDF5 Primary Antibody
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anti-Growth Differentiation Factor 5 (GDF5) (AA 358-495) antibody
GDF5 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 202-501) antibodyGDF5 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 382-501) antibodyGDF5 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (Internal Region) antibodyGDF5 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 28-127) antibodyGDF5 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1F4 unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 86-501) antibodyGDF5 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 13-41), (N-Term) antibodyGDF5 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB01877 unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 376-495) antibodyGDF5 Reactivity: Mouse IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 343-371), (C-Term) antibodyGDF5 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB31942 unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 350-450) antibodyGDF5 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB (H,M) 1:500-1:1000, IHC/IF (H,R) 1:200-1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- Alternative Name
- GDF 5 (GDF5 Products)
- Synonyms
- CDMP1 antibody, gdf antibody, gdf-5 antibody, GDF5 antibody, BDA1C antibody, BMP14 antibody, LAP4 antibody, OS5 antibody, SYM1B antibody, SYNS2 antibody, Cdmp-1 antibody, bp antibody, brp antibody, Cdmp1 antibody, growth differentiation factor 5 L homeolog antibody, growth differentiation factor 5 antibody, gdf5.L antibody, GDF5 antibody, Gdf5 antibody
- Background
- Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction . Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG . Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 .
- Molecular Weight
- 55 kDa
- Gene ID
- 14563
- NCBI Accession
- NP_032135
- UniProt
- P43027
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