IFIT3 antibody

Catalog No. ABIN7074333

Product Details anti-IFIT3 Antibody

Target: IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFIT3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse IFIT3/P60

Application Details

Application Notes: WB (H,M,R) 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IFIT3

Target: IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))

Alternative Name: IFIT3/P60 (IFIT3 Products)

Synonyms: DKFZp469G2233 antibody, CIG-49 antibody, GARG-49 antibody, IFI60 antibody, IFIT4 antibody, IRG2 antibody, ISG60 antibody, P60 antibody, RIG-G antibody, Ifi49 antibody, P49 antibody, IFIT-3 antibody, interferon induced protein with tetratricopeptide repeats 3 antibody, interferon-induced protein with tetratricopeptide repeats 3 antibody, IFIT3 antibody, Ifit3 antibody

Background: IFIT3 (IFN-induced protein with tetratricopeptide repeats 3), also known as IFIT-4, ISG-60 or RIG-G, is a 56 kDa IFN induced protein. IFIT3 has been identified to be associated with strong IFN antiviral activity. Upon RNA virus infection, IFIT3 is significantly induced, ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IFN regulatory factor 3 (IRF3)-mediated gene expression. IFIT3 thus may serve as an important modulator in innate immunity, revealing a new function of the IFIT family proteins.

Molecular Weight: 60 kDa

Gene ID: 15959

UniProt: Q64345