MIP antibody

Catalog No. ABIN7074547

Product Details anti-MIP Antibody

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human AQP0

Application Details

Application Notes: WB (M,R) 1:1000-1:3000, IHC/IF (M,R) 1:200-1:600/1:300-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MIP

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Alternative Name: AQP0 (MIP Products)

Synonyms: AQP0 antibody, CTRCT15 antibody, LIM1 antibody, MIP26 antibody, MP26 antibody, Aqp0 antibody, Cat antibody, Hfi antibody, Lop antibody, Svl antibody, shrivelled antibody, MP22 antibody, aqp0 antibody, lim1 antibody, mp26 antibody, mip26 antibody, MIP antibody, mip1 antibody, zgc:100858 antibody, mip2 antibody, zgc:110015 antibody, major intrinsic protein of lens fiber antibody, major intrinsic protein of lens fiber L homeolog antibody, major intrinsic protein of lens fiber a antibody, major intrinsic protein of lens fiber b antibody, MIP antibody, Mip antibody, mip.L antibody, mip antibody, mipa antibody, mipb antibody

Background: Aquaporin 0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 has been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80 % of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract. The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains.

Molecular Weight: 28 kDa

Gene ID: 17339

NCBI Accession: NP_036196

UniProt: P30301