MAL2 antibody
Quick Overview for MAL2 antibody (ABIN7074549)
Target
See all MAL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Rat
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Purification
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse MAL2
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Application Notes
- WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:300-1:1400/1:600-1:1600
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- MAL2 (Mal, T Cell Differentiation Protein 2 (MAL2))
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Alternative Name
- MAL2
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Background
- MAL2 (mal, T-cell differentiation protein 2) is a 176 amino acid multi-pass membrane protein that is associated with lipid rafts and contains one MARVEL domain. Expressed predominately in liver, kidney and lung, MAL2 functions as a member of the polarized machinery transport system and is required for transcytosis, a transporter pathway used to deliver membrane-bound cargo from perinuclear endosomes to the apical surface in a raft-dependent manner. Differential expression of MAL2 is associated with several cancers, including renal cell carcinoma and childhood leukemia, suggesting a role for MAL2 in tumorigensis.
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Molecular Weight
- 30 kDa
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Gene ID
- 105853
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NCBI Accession
- NP_849251
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UniProt
- Q8BI08
Target
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