MAL2 antibody

Catalog No. ABIN7074549

Product Details anti-MAL2 Antibody

Target: MAL2 (Mal, T Cell Differentiation Protein 2 (MAL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse MAL2

Application Details

Application Notes: WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:300-1:1400/1:600-1:1600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MAL2

Target: MAL2 (Mal, T Cell Differentiation Protein 2 (MAL2))

Alternative Name: MAL2 (MAL2 Products)

Synonyms: AI461653 antibody, mal, T cell differentiation protein 2 antibody, mal, T-cell differentiation protein 2 (gene/pseudogene) antibody, mal, T-cell differentiation protein 2 antibody, Mal2 antibody, MAL2 antibody

Background: MAL2 (mal, T-cell differentiation protein 2) is a 176 amino acid multi-pass membrane protein that is associated with lipid rafts and contains one MARVEL domain. Expressed predominately in liver, kidney and lung, MAL2 functions as a member of the polarized machinery transport system and is required for transcytosis, a transporter pathway used to deliver membrane-bound cargo from perinuclear endosomes to the apical surface in a raft-dependent manner. Differential expression of MAL2 is associated with several cancers, including renal cell carcinoma and childhood leukemia, suggesting a role for MAL2 in tumorigensis.

Molecular Weight: 30 kDa

Gene ID: 105853

NCBI Accession: NP_849251

UniProt: Q8BI08