MMP17 antibody
Quick Overview for MMP17 antibody (ABIN7074564)
Target
See all MMP17 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse MT4-MMP
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Application Notes
- WB (M,R) 1:1000-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
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Alternative Name
- MT4-MMP
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Background
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
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Molecular Weight
- 55 kDa
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Gene ID
- 23948
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UniProt
- Q9R0S3
Target
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