HLA-DP antibody

Catalog No. ABIN7074613

This anti-HLA-DP antibody is a Rabbit Polyclonal antibody detecting HLA-DP in IF and IHC. Suitable for Human.

Quick Overview for HLA-DP antibody (ABIN7074613)

Target: HLA-DP (MHC Class II HLA-DP (HLA-DP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DP antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-HLA-DP Antibody

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human HLA-DP

Application Details

Application Notes: IHC/IF (H) 1:1200-1:2400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for HLA-DP

Target: HLA-DP (MHC Class II HLA-DP (HLA-DP))

Alternative Name: HLA-DP

Background: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Gene ID: 3113

NCBI Accession: NP_001229453

UniProt: P20036