Neurturin antibody
Quick Overview for Neurturin antibody (ABIN7074832)
Target
See all Neurturin (NRTN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse Neurturin
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Application Notes
- IHC/IF (M,R) 1:500-1:1500/1:800-1:1600
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- Neurturin (NRTN)
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Alternative Name
- Neurturin
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Background
- Neurturin and GDNF define a new family of neurotrophic factors. Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. NTN binds to and forms a complex with GFR-a-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway.
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Gene ID
- 18188
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NCBI Accession
- NP_032764
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UniProt
- P97463
Target
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