Neurturin antibody (Internal Region)

Catalog No. ABIN7218792

This Rabbit Polyclonal antibody specifically detects Neurturin in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Neurturin antibody (Internal Region) (ABIN7218792)

Target: Neurturin (NRTN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurturin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Neurturin Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-NTN Polyclonal Antibody

Specificity: NTN Polyclonal Antibody detects endogenous levels of NTN protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NTN

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Neurturin

Target: Neurturin (NRTN)

Alternative Name: NTN

Background: NRTN, NeurturinNRTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Neurturin signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

Molecular Weight: 22kD

Gene ID: 4902

UniProt: Q99748