NOTCH3
Reactivity: Human
WB, ELISA, IF
Host: Mouse
Monoclonal
2E2
unconjugated
Application Notes
IHC/IF (M,R) 1:500-1:1500/1:500-1:1300
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target
NOTCH3
(Notch 3 (NOTCH3))
Alternative Name
NOTCH3
Background
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined.