Nucleolin antibody

Catalog No. ABIN7074906

The Rabbit Polyclonal anti-Nucleolin antibody is suitable to detect Nucleolin in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for Nucleolin antibody (ABIN7074906)

Target: Nucleolin (NCL)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nucleolin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Nucleolin Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Nucleolin

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:500-1:1000/1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Nucleolin

Target: Nucleolin (NCL)

Alternative Name: Nucleolin

Background: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

Molecular Weight: 110 kDa

Gene ID: 17975

NCBI Accession: NP_035010

UniProt: P09405

Pathways: Ribonucleoprotein Complex Subunit Organization