NUT antibody

Catalog No. ABIN7074932

Product Details

Target: NUT

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse NUT

Application Details

Application Notes: WB (H,R) 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details

Target: NUT

Synonyms: Nut antibody, RGD1564529 antibody, NUT midline carcinoma, family member 1 antibody, Nutm1 antibody

Background: Nuclear protein in testis is a 1,132 amino acid protein that is specifically expressed in testis. Belonging to the FAM22 family, NUT shuttles between nucleus and cytoplasm via a leptomycin-sensitive pathway. It is suggested that the translocation of the NUT gene is the cause of nuclear protein in testis midline carcinomas (NMC). NMCs are highly aggressive carcinomas typically arising in midline structures in young individuals.

Molecular Weight: 121 kDa

Gene ID: 213765

NCBI Accession: NP_766109

UniProt: Q8BHP2