PRR14 antibody

Catalog No. ABIN7075196

This Rabbit Polyclonal antibody specifically detects PRR14 in IF and IHC. It exhibits reactivity toward Mouse and Rat.

Quick Overview for PRR14 antibody (ABIN7075196)

Target: PRR14 (Proline Rich 14 (PRR14))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRR14 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-PRR14 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse PRR14

Application Details

Application Notes: IHC/IF (M,R) 1:1600-1:3200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PRR14

Target: PRR14 (Proline Rich 14 (PRR14))

Alternative Name: PRR14

Background: PRR14 (proline-rich protein 14) is a 585-amino acid protein with a calculated molecular weight of 64 kDa. This protein functions to tether heterochromatin to the nuclear periphery during interphase, through associations with heterochromatin protein 1 (HP1) and the nuclear lamina. After disassembly early in mitosis, PRR14 reassembles in two steps, first binding to anaphase chromosomes through HP1, followed by association with the nuclear lamina in telophase. PRR14 may thereby play a role in specifying HP1-bound heterochromatin for reattachment to the nuclear lamina at mitotic exit.

Gene ID: 233895

UniProt: Q7TPN9