ARHGAP17 antibody

Catalog No. ABIN7075416

The Rabbit Polyclonal anti-ARHGAP17 antibody has been validated for WB, IF and IHC. It is suitable to detect ARHGAP17 in samples from Rat and Mouse.

Quick Overview for ARHGAP17 antibody (ABIN7075416)

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP17 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-ARHGAP17 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse ARHGAP17

Application Details

Application Notes: WB (M) 1:250-1:500, IHC/IF (R) 1:500-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ARHGAP17

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Alternative Name: ARHGAP17

Background: ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Molecular Weight: 81 kDa

Gene ID: 70497

NCBI Accession: NP_001116112

UniProt: Q3UIA2