ARHGAP18 antibody

Catalog No. ABIN7075417

The Rabbit Polyclonal anti-ARHGAP18 antibody (ABIN7075417) specifically detects ARHGAP18 in WB, IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for ARHGAP18 antibody (ABIN7075417)

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ARHGAP18 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse ARHGAP18

Application Details

Application Notes: WB (H,M,R) 1:1000-1:1500, IHC/IF (M,R) 1:700-1:1400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ARHGAP18

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Alternative Name: ARHGAP18

Background: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.

Molecular Weight: 75 kDa

Gene ID: 73910

NCBI Accession: NP_789807

UniProt: Q8K0Q5