Slow Skeletal Myosin Heavy Chain antibody

Catalog No. ABIN7075623

The Rabbit Polyclonal anti-Slow Skeletal Myosin Heavy Chain antibody is suitable to detect Slow Skeletal Myosin Heavy Chain in samples from Mouse, Rat and Human. It has been validated for IF, IHC and WB.

Quick Overview for Slow Skeletal Myosin Heavy Chain antibody (ABIN7075623)

Target: Slow Skeletal Myosin Heavy Chain

Reactivity: Mouse, Rat, Human

Host: Rabbit

Clonality: Polyclonal

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Product Details

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to MYH7

Application Details

Application Notes: WB (M,R) 1:300-1:600, IHC/IF (H,M,R) 1:500-1:1000/1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details

Target: Slow Skeletal Myosin Heavy Chain

Background: This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading.

Molecular Weight: 223 kDa

Gene ID: 140781

NCBI Accession: NP_000248

UniProt: P12883