Tenascin R antibody
Quick Overview for Tenascin R antibody (ABIN7075858)
Target
See all Tenascin R (TNR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse TNR
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Application Notes
- WB (H,M,R) 1:300-1:600
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))
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Alternative Name
- TNR
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Background
- TNR, also named as Restrictin and Janusin, belongs to the tenascin family. Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides, TNR inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2 (FAK) phosphorylation and cell detachment.
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Molecular Weight
- 170 kDa
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Gene ID
- 21960
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NCBI Accession
- NP_071707
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UniProt
- Q8BYI9
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Pathways
- Regulation of Cell Size
Target
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