Cardiac Troponin T2 antibody

Catalog No. ABIN7076033

This Rabbit Polyclonal antibody specifically detects Cardiac Troponin T2 in IHC, IF and IEM. It exhibits reactivity toward Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for Cardiac Troponin T2 antibody (ABIN7076033)

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cardiac Troponin T2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoelectron Microscopy (IEM)

Product Details anti-Cardiac Troponin T2 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cardiac Troponin T

Application Details

Application Notes: IHC/IF ,IEM/M (M,R) 1:100-1:500/1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Cardiac Troponin T2 antibody (ABIN7076033)

Miao, Ding, Zou, Yang, Yang, Zhang, Li, Zhou, Zhang, Zhang, Du, Jiang, Zhou: "Inhibition of MyD88 by a novel inhibitor reverses two-thirds of the infarct area in myocardial ischemia and reperfusion injury." in: American journal of translational research, Vol. 12, Issue 9, pp. 5151-5169, (2020) (PubMed).

Target Details for Cardiac Troponin T2

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Alternative Name: Cardiac Troponin T

Background: As part of the Troponin complex, the function of cTnT is to regulate muscle contraction. The N-terminal region of TnT that strongly binds actin most likely moves with Tm and actin during strong myosin crossbridge binding and force generation. This region is likely involved in the transduction of cooperativity down the thin filament. The C-terminal region of TnT constitutes part of the globular troponin complex domain, and participates in employing the calcium sensitivity of strong myosin crossbridge binding to the thin filament.

Gene ID: 21956

NCBI Accession: NP_001123648

UniProt: P50752