UAP1L1 antibody

Catalog No. ABIN7076143

Product Details anti-UAP1L1 Antibody

Target: UAP1L1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1-Like 1 (UAP1L1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UAP1L1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse UAP1L1

Application Details

Application Notes: WB (M) 1:2000- 1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for UAP1L1

Target: UAP1L1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1-Like 1 (UAP1L1))

Alternative Name: UAP1L1 (UAP1L1 Products)

Synonyms: RP11-229P13.18 antibody, 5730445F03Rik antibody, zgc:56509 antibody, UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 antibody, UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 antibody, UDP-N-acetylglucosamine pyrophosphorylase 1, like 1 antibody, UAP1L1 antibody, Uap1l1 antibody, uap1l1 antibody

Background: UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.

Molecular Weight: 57 kDa

Gene ID: 227620

NCBI Accession: NP_001028465

UniProt: Q3TW96